Interactive Proteomics Data Sets
Momentum offers a range of proteomic and chemoproteomic services to advance your drug discovery research. Click around the data sets below to explore how quantitative proteomics can provide powerful biological insights. And, when you're ready, contact us to speak with an expert.
Momentum's proteomic and chemoproteomic services include: protein mass and purity analysis; protein identification; sequence confirmation; covalent modification mapping; covalent protein binding in vivo (ABPP); global quantitative profiling in vivo; kinase profiling in vivo; and PTM analysis in vivo.
The S-curve above highlights not only the sensitivity of the detection method
and the range of protein expression levels present in the sample,
but also the abundance of protein copies detected.
The CR plot above shows the ratio of DBIA-bound peptides
in inhibitor treated samples in comparison with DMSO controls.
The Volcano plot above illustrates the extent of peptide labeling in test versus control conditions.
Peptides showing a Log2 Ratio (DMSO/Inhibitor) >= 1 with p-values < 0.05
are considered differentially labeled by the inhibitor or "ligandable".
The heatmap above displays the ratio of DBIA-bound peptides for the protein of interest (POI),
KRAS, in inhibitor-treated samples compared to DMSO controls.
