QuantScout™

Targeted quantification of relevant proteoforms with maximum accuracy

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QuantScout™ enables accurate, sensitive and multiplexed quantification of up to 100 selected proteins and proteoforms across hundreds to thousands of samples, such as treated cell lines, cell line panels, xenograft models, or patient tissue and biofluid samples. This powerful targeted proteomics technology is based on Parallel Reaction Monitoring (PRM) and stable isotope labelled peptide standards, and is readily scalable to fit your experimental needs. QuantScout™ is a highly sensitive, antibody-independent assay that provides a powerful complement to discovery proteomics. This assay facilitates the translation of pre-clinical results into clinical innovations by validating predictive biomarkers, supporting targeted degrader development, and demonstrating target and pathway engagement. QuantScout™ can be used to quantify entire groups of proteins, such as cytokines, protein complexes, signaling sign-posts of selected pathways, metabolic enzymes, CYP450 oxidases and other drug-metabolizing enzymes

QuantScout™ technology can facilitate a variety of analyses, including:

  • Target engagement of covalent compounds
  • Pathway engagement of signaling drugs by analyzing modified proteoforms
  • Targeted protein degradation (PROTACs, molecular glue degraders)
  • Pharmacodynamic biomarker analyses
  • Differentiation of protein isoforms and mutants

Explore Other Technologies

Our technologies provide insight into protein abundance, activity, interactions, and more.

  • SignalingScout™

    Proteome-wide phosphorylation profiling

  • SPICE

    Label-free target profiling in cells with biophysical proteomics

  • SurfaceScout™

    Profiling of cell surface proteomes

  • TargetScout™

    Versatile, robust, and scalable platform for compound pulldowns

  • TurnoverScout™

    Global profiling of protein synthesis and degradation

  • UbiScout™

    Profiling of ubiquitination sites

  • CHIPP

    Sensitive, label-free, and scalable drug:target profiling

  • CysScout™

    Profiling of reactive cysteines

  • DecryptM

    Concentration-resolved PTM profiling

  • KinomeScout™

    Target profiling for kinases and other ATP-binding proteins

  • NucleoBeads™

    Identifying and characterizing functional inhibitors of DNA-binding proteins and transcription factors

  • PhotoTargetScout™

    Photo-affinity labeling and identification of compound-binding proteins

  • PlasmaScout™

    Clinical proteomics of plasma and serum proteins

  • Protein Turnover Atlas™

    On-demand access to protein turnover data

  • Proteome Atlas™

    Protein expression data across cell lines & tissues

  • ProteomeScout™

    Deep and rapid proteome profiling

Submit a Project Inquiry

To connect with our scientific team, submit a project inquiry. Our team will be in touch shortly to schedule an introductory meeting.

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