What can we help you with?

Services Phases

Services

Affinity Selection Mass SpectrometryAffinity Selection Mass SpectrometryCovalent Binding AssaysCovalent Binding AssaysProteomics & ChemoproteomicsProteomics & ChemoproteomicsSmall Molecule AnalysisSmall Molecule AnalysisOligo AnalysisOligo AnalysisData ProductsData ProductsView All ServicesView All Services

Phases

Target Discovery & ValidationTarget Discovery & ValidationLead GenerationLead GenerationLead Selection & OptimizationLead Selection & OptimizationPreclinical StudiesPreclinical StudiesBiomarker Discovery, Development & AnalysisBiomarker Discovery, Development & AnalysisView All PhasesView All Phases

What can we help you with?

Modalities Therapeutic Areas

Modalities

RadiotherapeuticsRadiotherapeuticsMolecular GluesMolecular GluesTargeted Protein DegradersTargeted Protein DegradersCovalent DrugsCovalent DrugsDNA- and RNA-Targeting DrugsDNA- and RNA-Targeting DrugsOligonucleotide TherapeuticsOligonucleotide TherapeuticsKinase InhibitorsKinase InhibitorsView All ModalitiesView All Modalities

Therapeutic Areas

OncologyOncologyImmunologyImmunologyNeuroscienceNeuroscienceMetabolic DiseaseMetabolic DiseaseInfectious DiseaseInfectious DiseaseRare DiseasesRare DiseasesView All Therapeutic AreasView All Therapeutic Areas

What can we help you with?

Technologies Platforms Expertise

Technologies

CHIPPCHIPPCysScout™CysScout™DecryptMDecryptMKinomeScout™KinomeScout™NucleoBeads™NucleoBeads™PhotoTargetScout™PhotoTargetScout™PlasmaScout™PlasmaScout™Protein Turnover Atlas™Protein Turnover Atlas™Proteome Atlas™Proteome Atlas™ProteomeScout™ProteomeScout™QuantScout™QuantScout™SignalingScout™SignalingScout™SPICESPICESurfaceScout™SurfaceScout™TargetScout™TargetScout™TurnoverScout™TurnoverScout™UbiScout™UbiScout™View All TechnologiesView All Technologies

Platforms

RapidFire-MSRapidFire-MSICP-MSICP-MSOrbitrap Astral ZoomOrbitrap Astral ZoomOrbitrap AscendOrbitrap AscendView All PlatformsView All Platforms

Expertise

Compound Management & Chemical LibrariesCompound Management & Chemical LibrariesScreening LaboratoryScreening LaboratoryBiochemistry & Chemical BiologyBiochemistry & Chemical BiologyCell & Molecular BiologyCell & Molecular BiologyMS-based ProteomicsMS-based ProteomicsComputational BiologyComputational BiologyProject ManagementProject ManagementView All ExpertiseView All Areas of Expertise

Biomarker Discovery, Development & Analysis

Identify and profile biomarkers with predictive, diagnostic, and prognostic value

Submit a project inquiry

Biomarker Discovery, Development & Analysis

Our services enable unbiased biomarker discovery, targeted biomarker discovery and development, and biomarker analysis of 100s to 10,000s of samples. We offer a flexible suite of quantitative multiplexed MS-based assays that can be tailored to project-specific requirements, ensuring superior identification and profiling of relevant biomarker candidates.

Over the past 10+ years, we have developed targeted assays for many important protein biomarkers, such as cytokines and peptide hormones, oncogenes, protein kinases, immuno-oncology-related proteins, as well as signaling sign-posts and numerous other classes of biomolecules. In addition to protein biomarkers, our HPLC-MS and RapidFire-MS technologies enable the quantitative analysis of lipids, amino acids, sugars, and metabolites.

We have the capability to support biomarker discovery, validation, development and analysis through:

  • Exploratory studies enabling unbiased discovery
  • Assay setup and development
  • Targeted validation

Frequently Asked Questions

What is a biomarker?

A biomarker refers to any measurable indicator that signifies a particular physiological process, disease state, or biological condition. Molecular biomarkers are often proteins but can also be lipids, sugars, and other biomolecules.

How are biomarkers used in drug discovery and development research?

Biomarkers can serve predictive, diagnostic, or prognostic roles and have significant value in both preclinical and clinical contexts. Pharmacodynamic biomarkers are used to measure the reactions of biological systems to pharmacological perturbations and are critical to demonstrating drug efficacy.

Can you profile cell surface biomarkers?

Our SurfaceScout™ workflow is specifically designed to profile cell surface proteins and provides a powerful approach for the discovery and validation of cell surface biomarkers.

Explore Other Phases

Our end-to-end service pipeline supports all phases of drug discovery and development.

  • Target Discovery & Validation

    Explore promising therapeutic targets and validate their relevance

  • Lead Generation

    Leverage high-throughput screening to discover lead compounds.

  • Lead Selection & Optimization

    Prioritize potential leads and optimize their activity

  • Preclinical Studies

    Comprehensively characterize drug activity, efficacy, and more

Submit a Project Inquiry

To connect with our scientific team, submit a project inquiry. Our team will be in touch shortly to schedule an introductory meeting.

Locations

United States

3 Federal Street, Suite 300
Billerica, MA 01821

Europe

Lise-Meitner-Strasse 30,
85354 Freising, Germany

Newsletter Signup

Sign up for News & Updates