Targeted Protein Degraders

Comprehensive services to support all steps of targeted protein degrader discovery and development

Targeted Protein Degradation is a powerful strategy that leverages endogenous cellular machineries to induce the specific degradation of a protein of interest (often via leveraging E3 ubiquitin ligase complexes and their target recognition subunits, such as CRBN or VHL). We offer a range of services to support the discovery and development of targeted protein degrader drugs, from the early stages of target selection through screening and preclinical characterization. By coupling our powerful high-throughput screening services with deep proteomic insights, we enable the efficient discovery and development of these potent therapeutics.