ProteomeScout™

Deep and rapid proteome profiling

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ProteomeScout™ technology enables the quantitative proteomic profiling of thousands of samples with unprecedented accuracy, precision, and depth (up to >10,000 proteins). Our automated 96-well plate workflow leverages data-independent acquisition (DIA) for label-free analysis and is readily scalable, allowing hundreds to thousands of compounds to be screened quickly and accurately. As a result, projects can often proceed from treated cells to reported data in less than two weeks, matching medchem development cycles and accelerating drug discovery efforts. These high-throughput capabilities facilitate rapid proteome-wide selectivity profiling for fast drug optimization iterations, provide valuable selectivity data early in compound development, and save significant time in the development of targeted protein degraders.

Our platform supports all major identification and quantification technologies, including:

  • Tandem Mass Tags®
  • Data-independent acquisition (DIA)
  • SILAC
  • AI-based peptide and protein ID tools

Our team has experience with all conceivable sample types

  • Fresh and frozen tissues
  • Body fluids
  • Formalin-fixed paraffin-embedded tissues
  • Cellular extracts, bacteria, plants, and more

Explore Other Technologies

Our technologies provide insight into protein abundance, activity, interactions, and more.

  • QuantScout™

    Targeted quantification of relevant proteoforms with maximum accuracy

  • SignalingScout™

    Proteome-wide phosphorylation profiling

  • SPICE

    Label-free target profiling in cells with biophysical proteomics

  • SurfaceScout™

    Profiling of cell surface proteomes

  • TargetScout™

    Versatile, robust, and scalable platform for compound pulldowns

  • TurnoverScout™

    Global profiling of protein synthesis and degradation

  • UbiScout™

    Profiling of ubiquitination sites

  • CHIPP

    Sensitive, label-free, and scalable drug:target profiling

  • CysScout™

    Profiling of reactive cysteines

  • DecryptM

    Concentration-resolved PTM profiling

  • KinomeScout™

    Target profiling for kinases and other ATP-binding proteins

  • NucleoBeads™

    Identifying and characterizing functional inhibitors of DNA-binding proteins and transcription factors

  • PhotoTargetScout™

    Photo-affinity labeling and identification of compound-binding proteins

  • PlasmaScout™

    Clinical proteomics of plasma and serum proteins

  • Protein Turnover Atlas™

    On-demand access to protein turnover data

  • Proteome Atlas™

    Protein expression data across cell lines & tissues

Submit a Project Inquiry

To connect with our scientific team, submit a project inquiry. Our team will be in touch shortly to schedule an introductory meeting.

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