ASMS Screening of the GLP1 Receptor

Intelligent Infusions Masterclass on ASMS small molecule screening and binding studies of the GLP1 receptor.

 

Click here to watch the full webinar. 

 

Key Takeaways:

• The NativeMP™ platform facilitates investigation of membrane proteins by effectively solubilizing and stabilizing target constructs.
• Affinity selection mass spectrometry (ASMS) is a powerful high-throughput screening technique used to identify small molecules that form non-covalent bonds with a target of interest.
• By leveraging NativeMP™ and a customized ASMS workflow, Cube Biotech and Momentum Biotechnologies successfully identified multiple small-molecule binders of the GLP1 receptor (GLP1R), an important target in the treatment of type 2 diabetes and obesity.