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What is ASMS? Affinity selection mass spectrometry (ASMS) is a powerful drug discovery technique that enables high-throughput screening of small molecule compounds against a wide range of targets. This technology offers several key advantages, including broad target compatibility, minimal assay development, and no requirement for target or compound labeling. In a typical ASMS experiment, compound libraries are screened against a protein target of interest to identify promising binders. However, ASMS is also extremely well suited for the screening of more specialized target types, such as RNA...

In a previous blog post, we explored how a comprehensive understanding of protein turnover dynamics can provide crucial...

In the drug discovery and development process, researchers aim to identify a compound that is active against a specific...

A recent article in Science Signaling shines a spotlight on the complex and interconnected world of oncogenic...

What is cell surface proteomics? Proteomics, or the comprehensive evaluation of the set of proteins present in a...

What are radiotherapeutics or radiopharmaceuticals? Radiopharmaceuticals, or medicinal compounds that contain...