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What is cell surface proteomics? Proteomics, or the comprehensive evaluation of the set of proteins present in a specific biological context, is a critical field that has become increasingly central to biological and pharmaceutical research, especially as technological advances enable these large-scale studies to be performed with increasing ease. One area of particular interest is cell surface proteomics or “surfaceomics,” which seeks to characterize and evaluate the suite of proteins present on the surfaces of various cell types under given conditions. Cell surface proteins carry out a...

What are radiotherapeutics or radiopharmaceuticals? Radiopharmaceuticals, or medicinal compounds that contain...

What is targeted quantitative proteomics? Targeted quantitative proteomics is a powerful approach to biochemical...

What is protein turnover? Protein levels within a cell are not fixed and invariant. Rather, they represent the net...

How are splicing modulators used therapeutically? As the world of small-molecule therapeutics continues to expand,...

What are microRNAs (miRNAs)? MicroRNAs (miRNAs) are a class of short noncoding RNAs that modulate gene expression...

Since January 2024, 46 novel drugs have been approved by the U.S. Food and Drug Administration (FDA), with roughly half...

What is ICP-MS? Inductively coupled plasma mass spectrometry (ICP-MS) is a powerful technique for the trace and...